Quick Details
CAS No.:62-57-7
Purity:98%
EINECS No.:200-544-0
MF:C4H9NO2
Other Names:2-Amino-2-methylpropionic acid; alpha-Aminoisobutyric acid; H-Aib-OH; 2-methylalanine;alpha-methylalanine; DL-2-Amino-iso-butanoic acid
Place of Origin:Shandong, China
Type:Syntheses Material Intermediates
2-Aminoisobutyric Acid (CAS no. 62-57-7) is one of the intermediates of enzalutamide, a second-generation small-molecule inhibitor of the androgen receptor (AR), has been approved for patients who failed with androgen deprivation therapy and have developed castration-resistant prostate cancer.
2-Aminoisobutyric acid exists in all living organisms, ranging from bacteria to humans. Outside of the human body, 2-Aminoisobutyric acid has been detected, but not quantified in, milk (cow). This could make 2-aminoisobutyric acid a potential biomarker for the consumption of these foods. Aminoisobutyric acid is a nonprotein amino acid (is an end product of pyrimidine metabolism) excreted in the urine of about 5% of healthy individuals , and high excretion is an autosomal recessive phenotype.
2-Aminoisobutyric acid, also known as alpha-methylalanine or a-aminoisobutanoate, belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). 2-Aminoisobutyric acid is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral.
Main Specification
Item | Specification | Result |
Appearance | White Crystal Powder | White Crystal Powder |
Identification | IR | Comply |
Loss on drying | ≤1.0% | 0.3% |
Purity(HPLC) | ≥98% | 99.3% |